Team	GS	W	G	V	P
1 San Antonio FC San Antonio FC	34	24	5	5	77
2 Louisville City FC Louisville City FC	34	22	6	6	72
3 Memphis 901 FC Memphis 901 FC	34	21	5	8	68
4 Tampa Bay Rowdies Tampa Bay Rowdies	34	20	7	7	67
5 San Diego Loyal SC San Diego Loyal SC	34	18	6	10	60
6 Birmingham Legion FC Birmingham Legion FC	34	17	7	10	58
7 Pittsburgh Riverhounds SC Pittsburgh Riverhounds SC	34	16	9	9	57
8 Colorado Springs Switchbacks FC Colorado Springs Switchbacks FC	34	17	4	13	55
9 Miami FC Miami FC	34	15	10	9	55
10 Detroit City FC Detroit City FC	34	14	12	8	54
11 Sacramento Republic FC Sacramento Republic FC	34	15	8	11	53
12 New Mexico United New Mexico United	34	13	12	9	51
13 Rio Grande Valley FC Rio Grande Valley FC	34	14	7	13	49
14 Oakland Roots SC Oakland Roots SC	34	11	13	10	46
15 El Paso Locomotive FC El Paso Locomotive FC	34	13	7	14	46
16 Las Vegas Lights FC Las Vegas Lights FC	34	12	9	13	45
17 Phoenix Rising FC Phoenix Rising FC	34	12	6	16	42
18 FC Tulsa FC Tulsa	34	12	6	16	42
19 Indy Eleven Indy Eleven	34	12	5	17	41
20 Ventura County FC Ventura County FC	34	11	7	16	40
21 Monterey Bay F.C. Monterey Bay F.C.	34	12	4	18	40
22 Hartford Athletic Hartford Athletic	34	10	6	18	36
23 Orange County SC Orange County SC	34	7	13	14	34
24 Loudoun United FC Loudoun United FC	34	8	4	22	28
25 Charleston Battery Charleston Battery	34	6	7	21	25
26 Atlanta United 2 Atlanta United 2	34	6	5	23	23
27 New York Red Bulls II New York Red Bulls II	34	3	6	25	15

Tampa Bay Rowdies - New York Red Bulls II

Op 15 oktober 2022 gaat Tampa Bay Rowdies de strijd aan met New York Red Bulls II. De wedstrijd wordt afgetrapt om 23:30 en wordt gespeeld in de USA 2.